Polynucleotide Therapy (PN / PDRN)
DNA-based regeneration that renews without adding volume.
Polynucleotide Therapy (PN/PDRN), commonly known as Salmon DNA Therapy, is a regenerative injectable treatment that uses highly purified polynucleotides derived from salmon DNA to support tissue repair and cellular regeneration. The treatment stimulates fibroblast activity, promotes collagen production, improves hydration, enhances skin elasticity and refines skin texture without adding volume. Patients often notice brighter, healthier and more luminous skin, making it an excellent option for overall skin rejuvenation, under-eye concerns and tissue repair. Polynucleotides may also be combined with other regenerative treatments, including calcium hydroxyapatite collagen stimulators, to further enhance results. Individual results vary.
Treatment focus
Tissue regeneration
Stimulating cellular renewal and supporting tissue repair through regenerative polynucleotides.
Tone & radiance
Improving hydration, skin luminosity and texture for healthier, brighter-looking skin.
Elasticity & collagen
Supporting collagen production and improving skin firmness and elasticity.
Cellular repair
Helping repair damaged tissues and restore overall skin quality and resilience.
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Salmon DNA technology
Uses highly purified polynucleotides, commonly known as Salmon DNA, to support the skin’s natural regeneration process.
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Natural skin rejuvenation
Improves hydration, brightness and tissue quality without changing facial volume or expression.
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Fibroblast stimulation
Supports collagen production and long-term improvements in elasticity and skin texture.
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Versatile application
Suitable for the face, under-eye area, neck, décolleté and scalp, depending on individual needs.
How your care works
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Consultation & assessment
Your treatment begins with a personalised assessment of your skin concerns, tissue quality and aesthetic goals, discussed during your consultation.
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Bespoke plan
A bespoke course of Polynucleotide Therapy (PN/PDRN) is recommended according to your individual needs and may be combined with other regenerative treatments when clinically appropriate.
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Treatment
Polynucleotides work to stimulate tissue repair, activate fibroblasts, improve hydration and support collagen production for healthier, brighter and more resilient skin.
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Ongoing renewal
Improvements in skin quality, brightness, elasticity and tissue regeneration continue progressively over time. Maintenance recommendations are discussed during your consultation.
- Face
- Under-eye rejuvenation
- Neck
- Décolleté
- Hands
- Acne scars
At Sol Clinic, Polynucleotide Therapy is integrated into personalised regenerative medicine programmes and is frequently combined with other collagen stimulation treatments, including calcium hydroxyapatite biostimulators, exosomes, PRP and advanced laser technologies when clinically appropriate. This combination approach helps optimise skin quality, improve tissue repair and enhance long-term regenerative outcomes.
Treatment investment
From £350
Individual sessions start from £350. Package pricing is available for patients requiring a course of treatment.
Book a private consultationBook a Private Consultation
Every treatment begins with a consultation and a detailed assessment. Speak with our team to arrange yours, handled with discretion.
